The relationship between mental experience and physical illness has never followed a simple historical line. Western medicine did not move neatly from ancient ‘holism’ to a Cartesian split and then back to modern integration. Different philosophical, religious and medical traditions have described the relationship in different ways, often at the same time.

Ancient medicine was not modern biopsychosocial care
Hippocratic and later humoral traditions considered diet, environment, temperament and bodily processes together, but their explanations were based on theories of humours and qualities that are not part of modern physiology. Calling this simply ‘holistic medicine’ risks projecting a contemporary category backwards.
Descartes did not single-handedly split medicine in two
René Descartes is important to the history of mind–body philosophy, but it is too strong to say his dualism became the direct bedrock of the biomedical model for centuries. Medical practice was shaped by many developments, including anatomy, pathology, laboratory science, institutions and changing theories of disease.
Psychological and physical processes can interact without implying that illness is ‘all in the mind’
Modern research examines interactions among the nervous, endocrine and immune systems, as well as the effects of behaviour and social conditions on health. These interactions do not mean psychological factors explain every symptom or disease. Biological disease should not be dismissed because stress or mental health may also influence a person’s experience.
The biopsychosocial model is a framework, not a universal mechanism
Contemporary healthcare often considers biological, psychological and social factors together. The relative importance of each varies enormously by condition and by individual. A fracture, an infection and chronic pain do not require the same explanatory balance.
The useful lesson from this history is not that medicine once ignored the mind and has now discovered a hidden unity. It is that concepts of illness change as evidence, institutions and social assumptions change.
This article is historical and conceptual. It does not suggest that physical symptoms should be attributed to psychological causes without appropriate medical assessment.

